Package: MBMethPred
Type: Package
Title: Medulloblastoma Subgroups Prediction
Version: 0.1.4.4
Date: 2025-12-04
Description: Utilizing a combination of machine learning models (Random Forest, Naive Bayes, K-Nearest Neighbor, Support Vector Machines, Extreme Gradient Boosting, and Linear Discriminant Analysis) and a deep Artificial Neural Network model, 'MBMethPred' can predict medulloblastoma subgroups, including wingless (WNT), sonic hedgehog (SHH), Group 3, and Group 4 from DNA methylation beta values. See Sharif Rahmani E, Lawarde A, Lingasamy P, Moreno SV, Salumets A and Modhukur V (2023), MBMethPred: a computational framework for the accurate classification of childhood medulloblastoma subgroups using data integration and AI-based approaches. Front. Genet. 14:1233657. <doi: 10.3389/fgene.2023.1233657> for more details.
Authors@R: c(
  person(given = "Edris", family = "Sharif Rahmani", email = "rahmani.biotech@gmail.com", role = c("aut", "ctb", "cre"), comment = c(ORCID = "0000-0002-7899-1663")),
  person(given = "Ankita", family = "Sunil Lawarde", email = "ankita.sunil.lawarde@ut.ee", role = c("aut", "ctb"), comment = c(ORCID = "0000-0001-7572-4431")),
  person(given = "Vijayachitra", family = "Modhukur", email = "vijayachitra.m@gmail.com", role = c("aut", "ctb"), comment = c(ORCID = "0000-0002-7123-9903")))
URL: https://github.com/sharifrahmanie/MBMethPred
Maintainer: Edris Sharif Rahmani <rahmani.biotech@gmail.com>
BugReports: https://github.com/sharifrahmanie/MBMethPred/issues
License: GPL
Encoding: UTF-8
LazyData: true
LazyDataCompression: xz
RoxygenNote: 7.2.3
Imports: stringr, ggplot2, parallel, caTools, caret, keras, MASS,
        Rtsne, SNFtool, class, dplyr, e1071, pROC, randomForest, readr,
        reshape2, reticulate, rgl, tensorflow, xgboost
Depends: R (>= 3.5.0)
Suggests: knitr, rmarkdown, testthat, utils, stats, scales
Config/testthat/edition: 3
VignetteBuilder: knitr
NeedsCompilation: no
Packaged: 2025-12-04 10:35:42 UTC; edi
Author: Edris Sharif Rahmani [aut, ctb, cre] (ORCID:
    <https://orcid.org/0000-0002-7899-1663>),
  Ankita Sunil Lawarde [aut, ctb] (ORCID:
    <https://orcid.org/0000-0001-7572-4431>),
  Vijayachitra Modhukur [aut, ctb] (ORCID:
    <https://orcid.org/0000-0002-7123-9903>)
Repository: CRAN
Date/Publication: 2025-12-04 11:00:02 UTC
Built: R 4.5.3; ; 2026-05-04 20:09:51 UTC; windows
